科研成果 | 深圳市药物成瘾重点实验室
科研成果

Zhou K, Zhu L, Hou G, Chen X, Chen B, Yang C, Zhu Y*. The Contribution of Thalamic Nuclei in Salience Processing. Front Behav Neurosci. 2021 Feb 16;15:634618.

Xu W, He Y, Zhang J, Li H, Wan X, Li M, Wang Y, Xu R, Zhang H, Dai Y, Liu H, Jiang L, Zhao Y, Cen X. Simvastatin Blocks Reinstatement of Cocaine-induced Conditioned Place Preference in Male Mice with Brain Lipidome Remodeling. Neurosci Bull. 2021 Dec;37(12):1683-1702.

Keyes, Piper; Adams, Eliza; Chen, Zijun; Bi, Linlin; Nachtrab, Gregory; Wang, Vickie; Tessier-Lavigne, Marc; Zhu, Yingjie*; Chen, Xiaoke*; Orchestrating Opiate-Associated Memories in Thalamic Circuits, Neuron, 2020, 107: 1–11 .

Zhou K; Zhu Y*; The paraventricular thalamic nucleus: A key hub of neural circuits underlying drug addiction, Pharmacol Res, 2019, 142:70-76.

Zhu Y; Nachtrab G; Keyes P; Allen W; Luo L; Chen X*; Dynamic Salience Processing in Paraventricular Thalamus Gates Associative Learning, Science,2018, 362(6413): 423-429

Zhu Y; Wienecke C; Nachtrab G; Chen X*; A thalamic input to the nucleus accumbens mediates opiate dependence, Nature, 2016, 530: 219-222. (Highlighted by Nature Reviews Neuroscience: Road to aversion)

Zhu Y#; Qiao W#; Liu K; Zhong H; Yao H*; Control of response reliability by parvalbumin-expressing interneurons in visual cortex, Nat. Commun, 2015, 6: 6802.

Zhu Y; Yao H*; Modification of visual cortical receptive field induced by natural stimuli, Cereb. Cortex, 2013, 23: 1923-1932.

Hailing Shi#; Xuliang Zhang#; Yi-Lan Weng#; Zongyang Lu; Yajing Liu; Zhike Lu; Jianan Li; Piliang Hao; Yu Zhang; Feng Zhang; You Wu; Jary Y. Delgado; Yijing Su; Meera Patel; Xiaohua Cao; Bin Shen; Xingxu Huang; Guo-li Ming; Xiaoxi Zhuang; Hongjun Song*; Chuan He*; Tao Zhou*; “m6A facilitates hippocampus-dependent learning and memory through Ythdf1”, Nature, 2018, 563:249-253.

Kun Li#; Tao Zhou#; Lujian Liao; Zhongfei Yang; Catherine Wong; Fritz Henn; Roberto Malinow; John R. Yates III; Hailan Hu*; “bCaMKII in Lateral Habenula Mediates Core Symptoms of Depression”. Science, 2013, 341(6149): 1016-20.

Ian A. Roundtree; Guan-Zheng Luo; Zijie Zhang; Xiao Wang; Tao Zhou; Yiqiang Cui; Jiahao Sha; Xingxu Huang; Laura Guerrero; Phil Xie; Emily He; Bin Shen; Chuan He*; “YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs”. eLife, 2017;6:e31311.

Jianbo Xiu#; Qi Zhang#; Tao Zhou; Tingting Zhou; Yang Chen; Hailan Hu*; “Visualizing an emotional valence map in the limbic forebrain by TAI-FISH”. Nature Neuroscience, 2014, 17 (11): 1552-1559.

  1. Wen Z. Yang#,*; Xiaosa Du#; Wen Zhang#; Cuicui Gao#; Hengchang Xie; Yan Xiao; Xiaoning Jia; Jiashu Liu; Jianhui Xu; Xin Fu; Hongqing Tu; Xiaoyu Fu; Xinyan Ni; Miao He; Jiajun Yang; Hong Wang; Haitao Yang; Xiao-hong Xu; Wei L Shen*; Parabrachial neuron types categorically encode thermoregulation variables during heat defense. Science Advances  2020 Sep: Vol. 6, no. 36.

     

Kun Song#, Hong Wang#, Gretel B Kamm#, Jörg Pohle, Fernanda de Castro Reis, PaulHeppenstall, Hagen Wende, and Jan Siemens*. The trpm2 channel is a hypothalamic heatsensor that limits fever and can drive hypothermia. Science, 2016 Sep 23;353(6306):1393-1398. 

Clemens AM, Lenschow C, Beed P, Li L, Sammons R, Naumann RK, Wang H, Schmitz D, Brecht M*, Estrus-Cycle Regulation of Cortical Inhibition. Current Biology. 2019 Feb 18;29(4):605-615.e6.

Hong Wang, Melanie Schupp, Sandra Zurborg, and Paul A Heppenstall*. Residues in the poreregion of drosophila transient receptor potential a1 dictate sensitivity to thermal stimuli. JPhysiol, 591(1):185–201, Jan 2013.

Hong Wang and Jan Siemens*. Trp ion channels in thermosensation, thermoregulation andmetabolism. Temperature (Austin), 2(2):178–187, 2015.

Laura Batti, MayyaSundukova, Emanuele Murana, SofiaPimpinella, Fernanda De Castro Reis,FrancescaPagani, Hong Wang, Eloisa Pellegrino, Emerald Perlas, Silvia Di Angelantonio, DavideRagozzino, and Paul A Heppenstall*. Tmem16f regulates spinal microglial function inneuropathic pain states. Cell Rep, 15(12):2608–2615, Jun 2016.

Meng Z, Berro LF, Sawyer EK, Ruedi-Betteschen D, Cook JE, Li G, Platt DM, Cook JM, Rowlett JK*. Evaluation of the anti-conflict, reinforcing, and sedative effects of YT-III-31, a ligand functionally selective for alpha3 subunit-containing GABAA receptors. Journal of Psychopharmacology, 2020;34(3):348-357.

Liu C#*, Meng Z#, Wiggin TD#, Yu J, Reed M, Guo F, Zhang Y, Rosbash M, Griffith LC*. A Serotonin-modulated circuit controls sleep architecture to regulate cognitive function independent of total sleep in Drosophila. Current Biology, 2019; 29: 3635–3646.

Duke AN#, Meng Z#, Platt DM, Atack JR, Dawson GR, Reynolds DS, Phani Babu Tiruveedhula VVN, Li GG, Stephen MR, Sieghart W, Cook JM, Rowlett JK*. Evidence that sedative effects of benzodiazepines involve unexpected GABAA receptor subtypes: quantitative observation studies in Rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics, 2018; 366:145-157.

Meng Z, Rowlett JK*. Self-administration of progesterone and synthetic neuroactive steroids by male rhesus monkeys. Drug and Alcohol Dependence, 2016; 165:265-9.

Meng Z*, Liu C, Yu C, Ma Y*. Transcranial direct current stimulation of the frontal-parietal-temporal area attenuates smoking behavior. Journal of Psychiatric Research, 2014; 54:19-25. (*co-corresponding author)

Duncan A#, Heyer MP#, Ishikawa M#, Caligiuri SPB#, Liu XA, Chen Z, Vittoria Micioni Di Bonaventura M, Elayouby KS, Ables JL, Howe WM, Bali P, Fillinger C, Williams M, O’Connor RM, Wang Z, Lu Q, Kamenecka TM, Ma’ayan A, O’Neill HC, Ibanez-Tallon I, Geurts AM, Kenny PJ*. Habenular TCF7L2 links nicotine addiction to diabetes. Nature 574(7778):372-377, 2019

Jia X; Liu XA; Shi Y; Yao S; Zhong X; Tian Y; Tian Q; Chen Z*; Wang L*. Profiling of key brain nuclei involved in CNS control of stress and glucose homeostasis. Biochem Biophys Res Commun, S0006-291X(19)31965-5, 2019

Chen, Z. & Kenny, P. J*. Endocannabinoid Signaling in the Habenula Regulates Adaptive Responses to Stress. Biol Psychiatry 84, 553-554, 2018

Tuesta LM, Chen Z, Duncan A, Fowler CD, Ishikawa M, Lee BR, Liu XA, Lu Q, Cameron M, Hayes MR, Kamenecka TM, Pletcher M, Kenny PJ*. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 2017

Chen, Z., Das, B., Nakamura, Y., DiGregorio, D. A. & Young, S. M., Jr*. Ca2+ channel to synaptic vesicle distance accounts for the readily releasable pool kinetics at a functionally mature auditory synapse. J Neurosci 35, 2083-2100, 2015

Passlick, S., Thapaliya, E. R., Chen, Z., Richers, M. T. & Ellis-Davies, G. C. R*. Optical probing of acetylcholine receptors on neurons in the medial habenula with a novel caged nicotine drug analogue. J Physiol 596, 5307-5318, 2018

Chen, Z. & Kenny, P. J*. Running on Empty: Leptin Signaling in VTA Regulates Reward from Physical Activity. Cell Metab 22, 540-541, 2015