成瘾与代谢及神经内分泌系统研究组
课题组长
王虹，博士，研究员，中科院“百人计划”获得者。2005年在北京大学获得学士学位，2012年在德国海德堡大学获得博士学位，并于2013-2017年继续在海德堡大学进行博士后研究。主要研究领域为中枢神经系统里下丘脑调控外周脏器功能的神经环路以及下丘脑调控代谢内稳态的机制。相关研究工作发表在Science等顶级期刊杂志。
研究方向
利用转基因动物研究成瘾模型中，代谢与神经内分泌系统的变化，为纠正内稳态的失衡提供实验和理论依据。
发表论文
(1) Wen Z. Yang#,*; Xiaosa Du#; Wen Zhang#; Cuicui Gao#; Hengchang Xie; Yan Xiao; Xiaoning Jia; Jiashu Liu; Jianhui Xu; Xin Fu; Hongqing Tu; Xiaoyu Fu; Xinyan Ni; Miao He; Jiajun Yang; Hong Wang; Haitao Yang; Xiao-hong Xu; Wei L Shen*; Parabrachial neuron types categorically encode thermoregulation variables during heat defense. Science Advances 2020 Sep: Vol. 6, no. 36.
(2) Clemens AM, Lenschow C, Beed P, Li L, Sammons R, Naumann RK, Wang H, Schmitz D, Brecht M*, Estrus-Cycle Regulation of Cortical Inhibition. Current Biology. 2019 Feb 18;29(4):605-615.e6.
(3) Kun Song#, Hong Wang#, Gretel B Kamm#, Jörg Pohle, Fernanda de Castro Reis, PaulHeppenstall, Hagen Wende, and Jan Siemens*. The trpm2 channel is a hypothalamic heatsensor that limits fever and can drive hypothermia. Science, 2016 Sep 23;353(6306):1393-1398.
(4) Laura Batti, MayyaSundukova, Emanuele Murana, SofiaPimpinella, Fernanda De Castro Reis,FrancescaPagani, Hong Wang, Eloisa Pellegrino, Emerald Perlas, Silvia Di Angelantonio, DavideRagozzino, and Paul A Heppenstall*. Tmem16f regulates spinal microglial function inneuropathic pain states. Cell Rep, 15(12):2608–2615, Jun 2016.
(5) Hong Wang and Jan Siemens*. Trp ion channels in thermosensation, thermoregulation andmetabolism. Temperature (Austin), 2(2):178–187, 2015.
(6) Hong Wang, Melanie Schupp, Sandra Zurborg, and Paul A Heppenstall*. Residues in the poreregion of drosophila transient receptor potential a1 dictate sensitivity to thermal stimuli. JPhysiol, 591(1):185–201, Jan 2013.
